Interleukin-1 receptor type 1

BE0000565ProteinHumansIL1R1

Receptor for IL1A, IL1B and IL1RN (PubMed:2950091, PubMed:37315560). It is acted on by 6 drugs in DrugBank.

Gene name
IL1R1
UniProtKB entry
P14778Swiss-Prot
Cellular location
Membrane
Residues / weight
569 residues · 65,402 Da
Also known as
3.2.2.6 · CD121 antigen-like family member A · IL-1R-1 · IL-1R-alpha · IL-1RT-1

Resolves to

Protein
UniProtP14778UniProt nameIL1R1_HUMAN
Gene
HGNCHGNC:5993NCBI Gene3554GenBank33801GeneCardsIL1R1
Pharmacology
IUPHAR/GtoPdb1734KEGGhsa:3554
Structure
PDB1G0YPDB1IRAPDB1ITB
Drugs

What you can answer from here — as of September 07, 2019

6DrugsApproved to experimental, with action, bond type and pharmacological action
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3Clinical trialsTrials of drugs acting on it, by phase and status
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16GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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28+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Interleukin-1 receptor type 1, how selective are they, and which programs against it are still in active trials?

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