AMG 108

DB05545InvestigationalProtein Based Therapies

AMG 108 was investigated for use as an antirheumatic agent.

Mechanism: Pharmacologically active on Interleukin-1 receptor type 1
Curator reviewed
Primary indication: Investigated for use/treatment in osteoarthritis and rheumatoid arthritis.Curator reviewed
Code names: AMG-108 · MEDI-78998 · MEDI-8968

Resolves to

Compound

Targets

What you can answer from here — as of June 15, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

381Drug interactionsStructured to mechanism, not free text

5Clinical trialsPhase, status and sponsor resolved per trial

4+ReferencesStructured and connected to the statements they support

Which drugs share a target with AMG 108, and which of those have an active Phase 3 trial?

Create a free account or log in to explore the full data card.