Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial
BE0000573ProteinHumansACADSB
Short and branched chain specific acyl-CoA dehydrogenase that catalyzes the proR-proR stereospecific alpha,beta-dehydrogenation of fatty acyl-CoA thioesters using the electron transfer flavoprotein (ETF) as their physiologic electron acceptor, resulting in the formation of trans-2-enoyl-CoA ((2E)-enoyl-CoA)... It is acted on by 2 drugs in DrugBank.
- Gene name
- ACADSB
- UniProtKB entry
- P45954Swiss-Prot
- Cellular location
- Mitochondrion matrix
- Residues / weight
- 432 residues · 47,485 Da
- Also known as
- 1.3.8.1 · 2-MEBCAD · 2-methyl branched chain acyl-CoA dehydrogenase · 2-methylbutyryl-CoA dehydrogenase · 2-methylbutyryl-coenzyme A dehydrogenase
Resolves to
Pharmacology
Structure
Drugs
What you can answer from here — as of September 07, 2019
Which approved drugs act on Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial, how selective are they, and which programs against it are still in active trials?
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