T-cell surface glycoprotein CD1a

BE0000598ProteinHumansCD1A

Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. It is acted on by 1 drug in DrugBank.

Gene name
CD1A
UniProtKB entry
P06126Swiss-Prot
Cellular location
Cell membrane
Residues / weight
327 residues · 37,077 Da
Also known as
hTa1 thymocyte antigen · T-cell surface antigen T6/Leu-6

Resolves to

Protein
UniProtP06126UniProt nameCD1A_HUMAN
Gene
HGNCHGNC:1634NCBI Gene909GenBank180036GeneCardsCD1A
Pharmacology
KEGGhsa:909
Structure
PDB1ONQPDB1XZ0PDB4X6C
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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3Clinical trialsTrials of drugs acting on it, by phase and status
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7GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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16+ReferencesStructured and connected to the statements they support
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Which approved drugs act on T-cell surface glycoprotein CD1a, how selective are they, and which programs against it are still in active trials?

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