Antithymocyte immunoglobulin (rabbit) is a purified form of rabbit anti-thymocyte antibodies used for immunosuppression in patients receiving kidney transplants. Thymoglobulin is a polyclonal antibody that suppresses certain types of immune cells responsible for acute organ rejection in transplant patients.
- Mechanism
- Curator reviewed
Binds to multiple, T-cell specific antigens leading to T-lymphocyte cell death via complement mediated cytotoxicity or apoptosis.
- Primary indication
- For prevention of renal transplant rejectionCurator reviewed · 2 structured indications
- First approval
- Canada, 2013 · United States, 1998
- Also known as
- Anti-human thymocyte immunoglobulin, rabbit · Anti-T-lymphocyte immune globulin, rabbit · Anti-thymocyte globulin (rabbit) · Anti-thymocyte globulin rabbit · Antithymocyte immunoglobulin
- Code names
- EZ-2053
Resolves to
Compound
Clinical / RWD
What you can answer from here — as of July 17, 2026
9Protein targetsEach mapped to UniProt, with action and pharmacological actionListed above
Which drugs share a target with Antithymocyte immunoglobulin (rabbit), and which of those have an active Phase 3 trial?
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