Glutamate decarboxylase 2

BE0000602ProteinHumansGAD2

Catalyzes the production of GABA. It is acted on by 2 drugs in DrugBank.

Gene name
GAD2
UniProtKB entry
Q05329Swiss-Prot
Cellular location
Cytoplasm, cytosol
Residues / weight
585 residues · 65,411 Da
Also known as
4.1.1.15 · 65 kDa glutamic acid decarboxylase · GAD-65 · GAD65 · Glutamate decarboxylase 65 kDa isoform

Resolves to

Protein
UniProtQ05329UniProt nameDCE2_HUMAN
Gene
HGNCHGNC:4093NCBI Gene2572GenBank182934GeneCardsGAD2
Pharmacology
KEGGhsa:2572
Structure
PDB1ES0PDB2OKKPDB7LZ6
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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18+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Glutamate decarboxylase 2, how selective are they, and which programs against it are still in active trials?

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