Glutamate--cysteine ligase regulatory subunit

BE0000606ProteinHumansGCLM

Glutamate--cysteine ligase regulatory subunit (Humans) is a protein target in DrugBank. It is acted on by 2 drugs in DrugBank.

Gene name
GCLM
UniProtKB entry
P48507Swiss-Prot
Residues / weight
274 residues · 30,727 Da
Also known as
Gamma-ECS regulatory subunit · Gamma-glutamylcysteine synthetase regulatory subunit · GCS light chain · GLCLR · Glutamate--cysteine ligase modifier subunit

Resolves to

Protein
UniProtP48507UniProt nameGSH0_HUMAN
Gene
HGNCHGNC:4312NCBI Gene2730GenBank530137GeneCardsGCLM
Pharmacology
KEGGhsa:2730
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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13GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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8+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Glutamate--cysteine ligase regulatory subunit, how selective are they, and which programs against it are still in active trials?

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