tRNA wybutosine-synthesizing protein 4

BE0000613ProteinHumansLCMT2

S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway (Probable). It is acted on by 1 drug in DrugBank.

Gene name
LCMT2
UniProtKB entry
O60294Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
686 residues · 75,601 Da
Also known as
2.1.1.290 · 2.3.1.231 · KIAA0547 · Leucine carboxyl methyltransferase 2 · tRNA yW-synthesizing protein 4

Resolves to

Protein
UniProtO60294UniProt nameTYW4_HUMAN
Gene
HGNCHGNC:17558NCBI Gene9836GenBank40788285GeneCardsLCMT2
Pharmacology
KEGGhsa:9836
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
2Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
5+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on tRNA wybutosine-synthesizing protein 4, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In