Growth hormone-releasing hormone receptor

BE0000625ProteinHumansGHRHR

Receptor for GRF, coupled to G proteins which activate adenylyl cyclase. It is acted on by 4 drugs in DrugBank.

Gene name
GHRHR
UniProtKB entry
Q02643Swiss-Prot
Cellular location
Cell membrane
Residues / weight
423 residues · 47,402 Da
Also known as
GHRH receptor · GRF receptor · GRFR · Growth hormone-releasing factor receptor

Resolves to

Protein
UniProtQ02643UniProt nameGHRHR_HUMAN
Gene
HGNCHGNC:4266NCBI Gene2692GenBank183173GeneCardsGHRHR
Pharmacology
IUPHAR/GtoPdb247KEGGhsa:2692
Structure
PDB2XDGPDB7CZ5
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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2Clinical trialsTrials of drugs acting on it, by phase and status
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21GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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17+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Growth hormone-releasing hormone receptor, how selective are they, and which programs against it are still in active trials?

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