Choline dehydrogenase, mitochondrial

BE0000636ProteinHumansCHDH

Catalyzes the dehydrogenation of choline to betaine aldehyde in the mitochondria (By similarity). It is acted on by 2 drugs in DrugBank.

Gene name
CHDH
UniProtKB entry
Q8NE62Swiss-Prot
Cellular location
Mitochondrion inner membrane
Residues / weight
594 residues · 65,358 Da
Also known as
1.1.99.1 · CDH · CHD

Resolves to

Protein
UniProtQ8NE62UniProt nameCHDH_HUMAN
Gene
HGNCHGNC:24288NCBI Gene55349GenBank21759795GeneCardsCHDH
Pharmacology
KEGGhsa:55349
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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13+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Choline dehydrogenase, mitochondrial, how selective are they, and which programs against it are still in active trials?

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