Choline salicylate is an anti-inflammatory pain reliever agent that is related to aspirin. It is used to decrease swelling and to treat mild-moderate pain. It is used to treat arthritis... This medicine can also be used for fever.
- Mechanism
- Curator reviewed · 3 references
Choline salicylate relieves pain by inhibition of prostaglandin synthesis and reduces fever by acting on the hypothalamus heat-regulating center. It also inhibits the generation of impulses through the inhibition of cyclooxygenase enzyme (COX).
Cyclooxygenase is involved in the production of prostaglandins, in response to injury and after various other stimuli. The prostaglandins promote pain, swelling, and inflammation. The choline salicylate decreases inflammation and pain by reducing the production of these prostaglandins in the area of the mouth it is applied to.
- Primary indication
- The oral gel is indicated for the relief of pain and discomfort of common mouth ulcers, cold sores, denture sore spots, infant teething and mouth ulcers, and sore spots due to orthodontic devices in children.Curator reviewed · 37 structured indications
- Formula / weight
- C12H19NO4 · 241.287 g/mol (avg)
- First approval
- Canada, 1965
Resolves to
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Which drugs share a target with Choline salicylate, and which of those have an active Phase 3 trial?
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