UMP-CMP kinase

BE0000637ProteinHumansCMPK1

Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. It is acted on by 8 drugs in DrugBank.

Gene name
CMPK1
UniProtKB entry
P30085Swiss-Prot
Cellular location
Nucleus
Residues / weight
196 residues · 22,222 Da
Also known as
2.7.4.14 · CK · CMK · CMPK · dCMP kinase

Resolves to

Protein
UniProtP30085UniProt nameKCY_HUMAN
Gene
HGNCHGNC:18170NCBI Gene51727GenBank6578133GeneCardsCMPK1
Pharmacology
KEGGhsa:51727
Structure
PDB1TEVPDB7E9V
Drugs

What you can answer from here — as of September 07, 2019

8DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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6Metabolic reactionsDrug transformations it catalyses, substrate to product
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10GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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29+ReferencesStructured and connected to the statements they support
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Which approved drugs act on UMP-CMP kinase, how selective are they, and which programs against it are still in active trials?

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