Folate receptor gamma

BE0000652ProteinHumansFOLR3

Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells. It is acted on by 2 drugs in DrugBank.

Gene name
FOLR3
UniProtKB entry
P41439Swiss-Prot
Cellular location
Secreted
Residues / weight
245 residues · 27,884 Da
Also known as
Folate receptor 3 · FR-gamma

Resolves to

Protein
UniProtP41439UniProt nameFOLR3_HUMAN
Gene
HGNCHGNC:3795NCBI Gene2352GenBank473236GeneCardsFOLR3
Pharmacology
KEGGhsa:2352
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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9+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Folate receptor gamma, how selective are they, and which programs against it are still in active trials?

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