Erythropoietin receptor

BE0000654ProteinHumansEPOR

Receptor for erythropoietin, which mediates erythropoietin-induced erythroblast proliferation and differentiation (PubMed:10388848, PubMed:2163695, PubMed:2163696, PubMed:8662939, PubMed:9774108). It is acted on by 10 drugs in DrugBank.

Gene name
EPOR
UniProtKB entry
P19235Swiss-Prot
Cellular location
Cell membrane
Residues / weight
508 residues · 55,065 Da
Also known as
EPO-R

Resolves to

Protein
UniProtP19235UniProt nameEPOR_HUMAN
Gene
HGNCHGNC:3416NCBI Gene2057GenBank182245GeneCardsEPOR
Pharmacology
IUPHAR/GtoPdb1718KEGGhsa:2057
Structure
PDB1CN4PDB1EBAPDB1EBP
Drugs

What you can answer from here — as of September 07, 2019

10DrugsApproved to experimental, with action, bond type and pharmacological action
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7Clinical trialsTrials of drugs acting on it, by phase and status
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4GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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50+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Erythropoietin receptor, how selective are they, and which programs against it are still in active trials?

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