Voltage-gated inwardly rectifying potassium channel KCNH7

BE0000699ProteinHumansKCNH7

Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel (PubMed:32723862). It is acted on by 2 drugs in DrugBank.

Gene name
KCNH7
UniProtKB entry
Q9NS40Swiss-Prot
Cellular location
Cell membrane
Residues / weight
1,196 residues · 134,999 Da
Also known as
Eag-related protein 3 · ERG-3 · ERG3 · Ether-a-go-go-related gene potassium channel 3 · Ether-a-go-go-related protein 3

Resolves to

Protein
UniProtQ9NS40UniProt nameKCNH7_HUMAN
Gene
HGNCHGNC:18863NCBI Gene90134GenBank4104136GeneCardsKCNH7
Pharmacology
KEGGhsa:90134
Structure
PDB6Y7Q
Drugs

What you can answer from here — as of October 08, 2024

2DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
4GO termsFunction, process and component, as structured annotations
Sign in
3Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
6+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Voltage-gated inwardly rectifying potassium channel KCNH7, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In