Urokinase plasminogen activator surface receptor

BE0000717ProteinHumansPLAUR

GPI-anchored receptor that recruits and activates the urokinase-type plasminogen activator (uPA) at the cell surface. It is acted on by 5 drugs in DrugBank.

Gene name
PLAUR
UniProtKB entry
Q03405Swiss-Prot
Cellular location
Cell membrane
Residues / weight
335 residues · 36,978 Da
Also known as
MO3 · Monocyte activation antigen Mo3 · U-PAR · UPAR

Resolves to

Protein
UniProtQ03405UniProt nameUPAR_HUMAN
Gene
HGNCHGNC:9053NCBI Gene5329GenBank37605GeneCardsPLAUR
Pharmacology
KEGGhsa:5329
Structure
PDB1YWHPDB2FD6PDB2I9B
Drugs

What you can answer from here — as of September 07, 2019

5DrugsApproved to experimental, with action, bond type and pharmacological action
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19GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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32+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Urokinase plasminogen activator surface receptor, how selective are they, and which programs against it are still in active trials?

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