Aldehyde dehydrogenase, dimeric NADP-preferring

BE0000718ProteinHumansALDH3A1

ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde (Probable). It is acted on by 3 drugs in DrugBank.

Gene name
ALDH3A1
UniProtKB entry
P30838Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
453 residues · 50,395 Da
Also known as
1.2.1.5 · Aldehyde dehydrogenase 3 · Aldehyde dehydrogenase family 3 member A1 · ALDH3 · ALDHIII

Resolves to

Protein
UniProtP30838UniProt nameAL3A1_HUMAN
Gene
HGNCHGNC:405NCBI Gene218GenBank178402GeneCardsALDH3A1
Pharmacology
KEGGhsa:218
Structure
PDB3SZAPDB3SZBPDB4H80
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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4Metabolic reactionsDrug transformations it catalyses, substrate to product
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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18+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Aldehyde dehydrogenase, dimeric NADP-preferring, how selective are they, and which programs against it are still in active trials?

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