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DB12083InvestigationalSmall molecule
Mafosfamide has been used in trials studying the treatment of Lymphoma, Leukemia, Meningeal Neoplasm, and Brain and Central Nervous System Tumors.
- Mechanism
- Curator reviewed
Pharmacologically active on Aldehyde dehydrogenase 1A1 and Aldehyde dehydrogenase, dimeric NADP-preferring
- Formula / weight
- C9H19Cl2N2O5PS2 · 401.25 g/mol (avg)
Resolves to
Structure
InChIKey
PBUUPFTVAPUWDE-UGZDLDLSSA-NSMILESOS(=O)(=O)CCS[C@H]1CCO[P@@](=O)(N1)N(CCCl)CCClTargets
What you can answer from here — as of October 13, 2026
Which drugs share a target with Mafosfamide, and which of those have an active Phase 3 trial?