Sodium-dependent proline transporter

BE0000723ProteinHumansSLC6A7

Brain specific sodium (and chloride)-dependent proline transporter (PubMed:7651355). It is acted on by 1 drug in DrugBank.

Gene name
SLC6A7
UniProtKB entry
Q99884Swiss-Prot
Cellular location
Synaptic cell membrane
Residues / weight
636 residues · 70,910 Da
Also known as
PROT · Solute carrier family 6 member 7

Resolves to

Protein
UniProtQ99884UniProt nameSC6A7_HUMAN
Gene
HGNCHGNC:11054NCBI Gene6534GenBank8176779GeneCardsSLC6A7
Pharmacology
IUPHAR/GtoPdb938KEGGhsa:6534
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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5+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Sodium-dependent proline transporter, how selective are they, and which programs against it are still in active trials?

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