Acetyl-coenzyme A synthetase 2-like, mitochondrial

BE0000746ProteinHumansACSS1

Catalyzes the synthesis of acetyl-CoA from short-chain fatty acids (PubMed:16788062). It is acted on by 1 drug in DrugBank.

Gene name
ACSS1
UniProtKB entry
Q9NUB1Swiss-Prot
Cellular location
Mitochondrion matrix
Residues / weight
689 residues · 74,856 Da
Also known as
6.2.1.1 · ACAS2L · AceCS2 · Acetate--CoA ligase 2 · Acetyl-CoA synthetase 2

Resolves to

Protein
UniProtQ9NUB1UniProt nameACS2L_HUMAN
Gene
HGNCHGNC:16091NCBI Gene84532GenBank56203090GeneCardsACSS1
Pharmacology
KEGGhsa:84532
Structure
PDB3GLRPDB3GLTPDB3GLU
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
4GO termsFunction, process and component, as structured annotations
Sign in
3Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
12+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Acetyl-coenzyme A synthetase 2-like, mitochondrial, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In