Oxytocin-neurophysin 1 proprotein

BE0000751ProteinHumansOXT

Precursor of oxytocin, a neurohypophyseal hormone that plays a key role in social interactions and neurophysin 1, its carrier protein. It is acted on by 1 drug in DrugBank.

Gene name
OXT
UniProtKB entry
P01178Swiss-Prot
Cellular location
Cytoplasmic vesicle, secretory vesicle
Residues / weight
125 residues · 12,722 Da
Also known as
OT · OT-NPI · pro-OXT · pro-oxytocin/neurophysin

Resolves to

Protein
UniProtP01178UniProt nameNEU1_HUMAN
Gene
HGNCHGNC:8528NCBI Gene5020GenBank189411GeneCardsOXT
Pharmacology
KEGGhsa:5020
Structure
PDB7OFGPDB7OTDPDB7QVM
Drugs

What you can answer from here — as of June 19, 2026

1DrugApproved to experimental, with action, bond type and pharmacological action
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4Clinical trialsTrials of drugs acting on it, by phase and status
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9GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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11+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Oxytocin-neurophysin 1 proprotein, how selective are they, and which programs against it are still in active trials?

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