Thromboxane A2 receptor

BE0000759ProteinHumansTBXA2R

Receptor for thromboxane A2 (TXA2), a potent stimulator of platelet aggregation. It is acted on by 20 drugs in DrugBank.

Gene name
TBXA2R
UniProtKB entry
P21731Swiss-Prot
Cellular location
Cell membrane
Residues / weight
343 residues · 37,431 Da
Also known as
Prostanoid TP receptor · TXA2-R

Resolves to

Protein
UniProtP21731UniProt nameTA2R_HUMAN
Gene
HGNCHGNC:11608NCBI Gene6915GenBank533326GeneCardsTBXA2R
Pharmacology
IUPHAR/GtoPdb346KEGGhsa:6915
Structure
PDB6IIUPDB6IIVPDB8XJN
Drugs

What you can answer from here — as of September 07, 2019

20DrugsApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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75+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Thromboxane A2 receptor, how selective are they, and which programs against it are still in active trials?

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