Short-chain specific acyl-CoA dehydrogenase, mitochondrial

BE0000762ProteinHumansACADS

Short-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation, an aerobic process breaking down fatty acids into acetyl-CoA and allowing the production of energy... It is acted on by 3 drugs in DrugBank.

Gene name
ACADS
UniProtKB entry
P16219Swiss-Prot
Cellular location
Mitochondrion matrix
Residues / weight
412 residues · 44,297 Da
Also known as
1.3.8.1 · Butyryl-CoA dehydrogenase · SCAD

Resolves to

Protein
UniProtP16219UniProt nameACADS_HUMAN
Gene
HGNCHGNC:90NCBI Gene35GenBank337928GeneCardsACADS
Pharmacology
KEGGhsa:35
Structure
PDB2VIGPDB7Y0APDB7Y0B
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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14+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Short-chain specific acyl-CoA dehydrogenase, mitochondrial, how selective are they, and which programs against it are still in active trials?

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