Glutathione S-transferase theta-1

BE0000818ProteinHumansGSTT1

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. It is acted on by 6 drugs in DrugBank.

Gene name
GSTT1
UniProtKB entry
P30711Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
240 residues · 27,335 Da
Also known as
2.5.1.18 · Glutathione transferase T1-1 · GST class-theta-1

Resolves to

Protein
UniProtP30711UniProt nameGSTT1_HUMAN
Gene
HGNCHGNC:4641NCBI Gene2952GenBank510905GeneCardsGSTT1
Pharmacology
KEGGhsa:2952
Structure
PDB2C3NPDB2C3QPDB2C3T
Drugs

What you can answer from here — as of September 07, 2019

6DrugsApproved to experimental, with action, bond type and pharmacological action
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2Clinical trialsTrials of drugs acting on it, by phase and status
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1Metabolic reactionDrug transformations it catalyses, substrate to product
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1GO termFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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23+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Glutathione S-transferase theta-1, how selective are they, and which programs against it are still in active trials?

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