Metabotropic glutamate receptor 8

BE0000835ProteinHumansGRM8

G protein-coupled receptor for glutamate. It is acted on by 1 drug in DrugBank.

Gene name
GRM8
UniProtKB entry
O00222Swiss-Prot
Cellular location
Cell membrane
Residues / weight
908 residues · 101,740 Da
Also known as
GPRC1H · MGLUR8

Resolves to

Protein
UniProtO00222UniProt nameGRM8_HUMAN
Gene
HGNCHGNC:4600NCBI Gene2918GenBank1935043GeneCardsGRM8
Pharmacology
IUPHAR/GtoPdb296KEGGhsa:2918
Structure
PDB6BSZPDB6BT5PDB6E5V
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Metabotropic glutamate receptor 8, how selective are they, and which programs against it are still in active trials?

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