Large ribosomal subunit protein uL3

BE0000843ProteinStreptococcus pyogenes serotype M1rplC

One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. It is acted on by 2 drugs in DrugBank.

Gene name
rplC
UniProtKB entry
Q9A1X4Swiss-Prot
Residues / weight
208 residues · 22,438 Da
Also known as
50S ribosomal protein L3

Resolves to

Protein
UniProtQ9A1X4UniProt nameRL3_STRP1
Gene
NCBI Gene900403GenBank13621367
Pharmacology
KEGGspy:SPy_0049
Drugs

What you can answer from here — as of May 03, 2025

2DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
4GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
9+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Large ribosomal subunit protein uL3, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In