Platelet glycoprotein IX

BE0000866ProteinHumansGP9

The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. It is acted on by 1 drug in DrugBank.

Gene name
GP9
UniProtKB entry
P14770Swiss-Prot
Cellular location
Membrane
Residues / weight
177 residues · 19,046 Da
Also known as
Glycoprotein 9 · GP-IX · GPIX

Resolves to

Protein
UniProtP14770UniProt nameGPIX_HUMAN
Gene
HGNCHGNC:4444NCBI Gene2815GenBank2160046GeneCardsGP9
Pharmacology
KEGGhsa:2815
Structure
PDB3REZPDB8WFS
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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15+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Platelet glycoprotein IX, how selective are they, and which programs against it are still in active trials?

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