Cocaine- and amphetamine-regulated transcript protein

BE0000867ProteinHumansCARTPT

Satiety factor closely associated with the actions of leptin and neuropeptide Y; this anorectic peptide inhibits both normal and starvation-induced feeding and completely blocks the feeding response induced by neuropeptide Y and regulated by leptin... It is acted on by 1 drug in DrugBank.

Gene name
CARTPT
UniProtKB entry
Q16568Swiss-Prot
Cellular location
Secreted
Residues / weight
116 residues · 12,829 Da
Also known as
CART

Resolves to

Protein
UniProtQ16568UniProt nameCART_HUMAN
Gene
HGNCHGNC:24323NCBI Gene9607GenBank609306GeneCardsCARTPT
Pharmacology
KEGGhsa:9607
Structure
PDB1HY9
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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15GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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13+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Cocaine- and amphetamine-regulated transcript protein, how selective are they, and which programs against it are still in active trials?

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