Histone deacetylase 9

BE0000881ProteinHumansHDAC9

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). It is acted on by 2 drugs in DrugBank.

Gene name
HDAC9
UniProtKB entry
Q9UKV0Swiss-Prot
Cellular location
Nucleus
Residues / weight
1,011 residues · 111,296 Da
Also known as
3.5.1.98 · HD7 · HD7b · HD9 · HDAC7

Resolves to

Protein
UniProtQ9UKV0UniProt nameHDAC9_HUMAN
Gene
HGNCHGNC:14065NCBI Gene9734GenBank15590680GeneCardsHDAC9
Pharmacology
IUPHAR/GtoPdb2620KEGGhsa:9734
Structure
PDB8Q9NPDB8Q9R
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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17GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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27+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Histone deacetylase 9, how selective are they, and which programs against it are still in active trials?

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