Peroxiredoxin-5, mitochondrial

BE0000907ProteinHumansPRDX5

Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. It is acted on by 5 drugs in DrugBank.

Gene name
PRDX5
UniProtKB entry
P30044Swiss-Prot
Cellular location
Mitochondrion
Residues / weight
214 residues · 22,086 Da
Also known as
1.11.1.24 · ACR1 · Alu corepressor 1 · Antioxidant enzyme B166 · AOEB166

Resolves to

Protein
UniProtP30044UniProt namePRDX5_HUMAN
Gene
HGNCHGNC:9355NCBI Gene25824GenBank6523289GeneCardsPRDX5
Pharmacology
KEGGhsa:25824
Structure
PDB1H4OPDB1HD2PDB1OC3
Drugs

What you can answer from here — as of September 07, 2019

5DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
24GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
28+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Peroxiredoxin-5, mitochondrial, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In