Triptolide

DB12025InvestigationalSmall molecule

Triptolide has been used in trials studying the treatment of HIV, Crohn's Disease, Intestinal Diseases, Gastrointestinal Diseases, and Digestive System Diseases, among others.

Formula / weight: C₂₀H₂₄O₆ · 360.406 g/mol (avg)

Resolves to

Compound

UNII19ALD1S53JCAS38748-32-2ChEMBLCHEMBL463763ChEBI9747PubChem107985KEGGC09204

Structure

InChIKeyDFBIRQPKNDILPW-CIVMWXNOSA-NSMILESCC(C)[C@]12O[C@H]1[C@@H]1O[C@]11[C@]3(O[C@H]3C[C@H]3C4=C(CC[C@]13C)C(=O)OC4)[C@@H]2O

Targets

P30044PRDX5Q04864RELQ01201RELBQ04206RELAQ00653NFKB2P19838NFKB1

What you can answer from here — as of April 02, 2025

6Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

400Drug interactionsStructured to mechanism, not free text

9Clinical trialsPhase, status and sponsor resolved per trial

6+ReferencesStructured and connected to the statements they support

Which drugs share a target with Triptolide, and which of those have an active Phase 3 trial?

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