Sodium- and chloride-dependent glycine transporter 1

BE0000940ProteinHumansSLC6A9

Sodium- and chloride-dependent glycine transporter (PubMed:37962965, PubMed:8183239). It is acted on by 7 drugs in DrugBank.

Gene name
SLC6A9
UniProtKB entry
P48067Swiss-Prot
Cellular location
Cell membrane
Residues / weight
706 residues · 78,260 Da
Also known as
GlyT-1 · GlyT1 · Solute carrier family 6 member 9

Resolves to

Protein
UniProtP48067UniProt nameSC6A9_HUMAN
Gene
HGNCHGNC:11056NCBI Gene6536GenBank546769GeneCardsSLC6A9
Pharmacology
IUPHAR/GtoPdb935KEGGhsa:6536
Structure
PDB6ZBVPDB6ZPLPDB8WFI
Drugs

What you can answer from here — as of September 07, 2019

7DrugsApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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26+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Sodium- and chloride-dependent glycine transporter 1, how selective are they, and which programs against it are still in active trials?

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