Myeloblastin

BE0000954ProteinHumansPRTN3

Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) (PubMed:2033050, PubMed:28240246, PubMed:3198760). It is acted on by 4 drugs in DrugBank.

Gene name
PRTN3
UniProtKB entry
P24158Swiss-Prot
Cellular location
Cytoplasmic granule
Residues / weight
256 residues · 27,807 Da
Also known as
3.4.21.76 · AGP7 · C-ANCA antigen · Leukocyte proteinase 3 · MBN

Resolves to

Protein
UniProtP24158UniProt namePRTN3_HUMAN
Gene
HGNCHGNC:9495NCBI Gene5657GenBank187399GeneCardsPRTN3
Pharmacology
IUPHAR/GtoPdb2401KEGGhsa:5657
Structure
PDB1FUJ
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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2Clinical trialsTrials of drugs acting on it, by phase and status
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11GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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28+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Myeloblastin, and which indications are they being tested in?

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