Synaptic vesicle glycoprotein 2A

BE0000993ProteinHumansSV2A

Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. It is acted on by 4 drugs in DrugBank.

Gene name
SV2A
UniProtKB entry
Q7L0J3Swiss-Prot
Cellular location
Presynapse
Residues / weight
742 residues · 82,695 Da
Also known as
KIAA0736

Resolves to

Protein
UniProtQ7L0J3UniProt nameSV2A_HUMAN
Gene
HGNCHGNC:20566NCBI Gene9900GenBank40788343GeneCardsSV2A
Pharmacology
KEGGhsa:9900
Structure
PDB4V11PDB8JLCPDB8JLE
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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3Clinical trialsTrials of drugs acting on it, by phase and status
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9GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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20+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Synaptic vesicle glycoprotein 2A, how selective are they, and which programs against it are still in active trials?

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