C-C motif chemokine 2

BE0001047ProteinHumansCCL2

Acts as a ligand for C-C chemokine receptor CCR2 (PubMed:10529171, PubMed:10587439, PubMed:9837883). It is acted on by 5 drugs in DrugBank.

Gene name
CCL2
UniProtKB entry
P13500Swiss-Prot
Cellular location
Secreted
Residues / weight
99 residues · 11,025 Da
Also known as
HC11 · MCAF · MCP-1 · MCP1 · Monocyte chemoattractant protein 1

Resolves to

Protein
UniProtP13500UniProt nameCCL2_HUMAN
Gene
HGNCHGNC:10618NCBI Gene6347GenBank307163GeneCardsCCL2
Pharmacology
KEGGhsa:6347
Structure
PDB1DOKPDB1DOLPDB1DOM
Drugs

What you can answer from here — as of September 07, 2019

5DrugsApproved to experimental, with action, bond type and pharmacological action
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13Clinical trialsTrials of drugs acting on it, by phase and status
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39GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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34+ReferencesStructured and connected to the statements they support
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Which approved drugs act on C-C motif chemokine 2, how selective are they, and which programs against it are still in active trials?

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