Angiotensinogen

BE0001060ProteinHumansAGT

Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. It is acted on by 6 drugs in DrugBank.

Gene name
AGT
UniProtKB entry
P01019Swiss-Prot
Cellular location
Secreted
Residues / weight
476 residues · 52,069 Da
Also known as
Serpin A8 · SERPINA8

Resolves to

Protein
UniProtP01019UniProt nameANGT_HUMAN
Gene
HGNCHGNC:333NCBI Gene183GenBank178640GeneCardsAGT
Pharmacology
KEGGhsa:183
Structure
PDB1N9UPDB1N9VPDB2JP8
Drugs

What you can answer from here — as of September 07, 2019

6DrugsApproved to experimental, with action, bond type and pharmacological action
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5Clinical trialsTrials of drugs acting on it, by phase and status
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16GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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40+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Angiotensinogen, how selective are they, and which programs against it are still in active trials?

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