Major prion protein

BE0001105ProteinHumansPRNP

Its primary physiological function is unclear. It is acted on by 4 drugs in DrugBank.

Gene name
PRNP
UniProtKB entry
P04156Swiss-Prot
Cellular location
Cell membrane
Residues / weight
253 residues · 27,661 Da
Also known as
ALTPRP · ASCR · PRIP · PRP · PrP27-30

Resolves to

Protein
UniProtP04156UniProt namePRIO_HUMAN
Gene
HGNCHGNC:9449NCBI Gene5621GenBank190468GeneCardsPRNP
Pharmacology
KEGGhsa:5621
Structure
PDB1E1GPDB1E1JPDB1E1P
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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25GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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67+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Major prion protein, how selective are they, and which programs against it are still in active trials?

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