Carbon black
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Explore a selection of our essential drug information below, or:
Identification
- Generic Name
- Carbon black
- DrugBank Accession Number
- DB11980
- Background
Produced by the incomplete combustion of hydrocarbons, carbon black is an insoluble pigment 1 with demonstrated adverse effects on pulmonary function.2 Upon inhalation, carbon black has been reported to trigger an inflammatory response in the lung tissue 2 and has been linked to carcinogenicity.3,4,5
- Type
- Small Molecule
- Groups
- Investigational
- Structure
- Weight
- Average: 12.011
Monoisotopic: 12.0 - Chemical Formula
- C
- Synonyms
- BLACK 2
- C.I. 77266
- C.I. PIGMENT BLACK 7
- CI 77266
- D&C black no. 2
- D&C BLACK NO. 2 [II]
- DC BLACK NO. 2
- VEGETABLE CARBON
- VEGETABLE CARBON (E 153)
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Categories
- Drug Categories
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of organic compounds known as organic compounds. These are compounds that contain at least one carbon atom, excluding isocyanide/cyanide and their non-hydrocarbyl derivatives, thiophosgene, carbon diselenide, carbon monosulfide, carbon disulfide, carbon subsulfide, carbon monoxide, carbon trioxide, carbon suboxide, and dicarbon monoxide.
- Kingdom
- Organic compounds
- Super Class
- Not Available
- Class
- Not Available
- Sub Class
- Not Available
- Direct Parent
- Organic compounds
- Alternative Parents
- Not Available
- Substituents
- Aliphatic acyclic compound / Organic compound
- Molecular Framework
- Aliphatic acyclic compounds
- External Descriptors
- nonmetal atom, carbon group element atom (CHEBI:27594)
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 4XYU5U00C4
- CAS number
- 1333-86-4
- InChI Key
- OKTJSMMVPCPJKN-UHFFFAOYSA-N
- InChI
- InChI=1S/C
- IUPAC Name
- carbon
- SMILES
- [C]
References
- General References
- Miranda-Bermudez E, Belai N, Harp BP, Yakes BJ, Barrows JN: Qualitative determination of carbon black in food products. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2012;29(1):38-42. doi: 10.1080/19440049.2011.616535. Epub 2011 Oct 31. [Article]
- Zhang H, Lou N, Liu XY, Li CZ, Xu K, Xu FF, Su AC, Zhang LY, Zhang M, Zhang JG: Long-term carbon black inhalation induced the inflammation and autophagy of cerebellum in rats. Neurotoxicology. 2021 Dec;87:120-127. doi: 10.1016/j.neuro.2021.08.019. Epub 2021 Sep 9. [Article]
- Zhang J, Li X, Cheng W, Li Y, Shi T, Jiang Y, Wang T, Wang H, Ren D, Zhang R, Zheng Y, Tang J: Chronic carbon black nanoparticles exposure increases lung cancer risk by affecting the cell cycle via circulatory inflammation. Environ Pollut. 2022 Jul 15;305:119293. doi: 10.1016/j.envpol.2022.119293. Epub 2022 Apr 11. [Article]
- Chang CY, You R, Armstrong D, Bandi A, Cheng YT, Burkhardt PM, Becerra-Dominguez L, Madison MC, Tung HY, Zeng Z, Wu Y, Song L, Phillips PE, Porter P, Knight JM, Putluri N, Yuan X, Marcano DC, McHugh EA, Tour JM, Catic A, Maneix L, Burt BM, Lee HS, Corry DB, Kheradmand F: Chronic exposure to carbon black ultrafine particles reprograms macrophage metabolism and accelerates lung cancer. Sci Adv. 2022 Nov 18;8(46):eabq0615. doi: 10.1126/sciadv.abq0615. Epub 2022 Nov 16. [Article]
- McCunney RJ, Morfeld P, Levy L, Muranko H: Carbon black. Environ Health Perspect. 2011 Aug;119(8):A332-3; author reply A333-4. doi: 10.1289/ehp.1103444. [Article]
- External Links
- PubChem Substance
- 347828302
- 2032
- Wikipedia
- Carbon_black
Clinical Trials
- Clinical Trials
Clinical Trial & Rare Diseases Add-on Data Package
Explore 4,000+ rare diseases, orphan drugs & condition pairs, clinical trial why stopped data, & more. Preview package Phase Status Purpose Conditions Count Start Date Why Stopped 100+ additional columns Unlock 175K+ rows when you subscribe.View sample data1 Completed Not Available Atopic Hypersensitivity / Type I Hypersensitivity 1 somestatus stop reason just information to hide
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Solid
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source logP 0 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 0 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 0 Å2 Chemaxon Rotatable Bond Count 0 Chemaxon Refractivity 13.11 m3·mol-1 Chemaxon Polarizability 1.51 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Chromatographic Properties
Collision Cross Sections (CCS)
Adduct CCS Value (Å2) Source type Source [M-H]- 109.33826 predictedDeepCCS 1.0 (2019) [M+H]+ 111.11545 predictedDeepCCS 1.0 (2019) [M+Na]+ 117.95068 predictedDeepCCS 1.0 (2019)
Drug created at October 20, 2016 21:07 / Updated at October 21, 2024 12:40