Vascular cell adhesion protein 1

BE0001114ProteinHumansVCAM1

Cell adhesion glycoprotein predominantly expressed on the surface of endothelial cells that plays an important role in immune surveillance and inflammation (PubMed:31310649). It is acted on by 6 drugs in DrugBank.

Gene name
VCAM1
UniProtKB entry
P19320Swiss-Prot
Cellular location
Cell membrane
Residues / weight
739 residues · 81,275 Da
Also known as
INCAM-100 · V-CAM 1 · VCAM-1

Resolves to

Protein
UniProtP19320UniProt nameVCAM1_HUMAN
Gene
HGNCHGNC:12663NCBI Gene7412GenBank179886GeneCardsVCAM1
Pharmacology
KEGGhsa:7412
Structure
PDB1IJ9PDB1VCAPDB1VSC
Drugs

What you can answer from here — as of September 07, 2019

6DrugsApproved to experimental, with action, bond type and pharmacological action
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8Clinical trialsTrials of drugs acting on it, by phase and status
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22GO termsFunction, process and component, as structured annotations
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4Pfam domainsDomain architecture mapped to Pfam families and clans
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22+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Vascular cell adhesion protein 1, how selective are they, and which programs against it are still in active trials?

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