Hepatocyte growth factor

BE0001121ProteinHumansHGF

Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types (PubMed:20624990). It is acted on by 10 drugs in DrugBank.

Gene name
HGF
UniProtKB entry
P14210Swiss-Prot
Residues / weight
728 residues · 83,133 Da
Also known as
Hepatopoietin-A · HPTA · Scatter factor · SF

Resolves to

Protein
UniProtP14210UniProt nameHGF_HUMAN
Gene
HGNCHGNC:4893NCBI Gene3082GenBank306846GeneCardsHGF
Pharmacology
KEGGhsa:3082
Structure
PDB1BHTPDB1GMNPDB1GMO
Drugs

What you can answer from here — as of September 07, 2019

10DrugsApproved to experimental, with action, bond type and pharmacological action
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15Clinical trialsTrials of drugs acting on it, by phase and status
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6GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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39+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Hepatocyte growth factor, how selective are they, and which programs against it are still in active trials?

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