Carboxypeptidase E

BE0001123ProteinHumansCPE

Sorting receptor that directs prohormones to the regulated secretory pathway. It is acted on by 4 drugs in DrugBank.

Gene name
CPE
UniProtKB entry
P16870Swiss-Prot
Cellular location
Cytoplasmic vesicle, secretory vesicle
Residues / weight
476 residues · 53,150 Da
Also known as
3.4.17.10 · Carboxypeptidase H · CPE · CPH · Enkephalin convertase

Resolves to

Protein
UniProtP16870UniProt nameCBPE_HUMAN
Gene
HGNCHGNC:2303NCBI Gene1363GenBank29667GeneCardsCPE
Pharmacology
KEGGhsa:1363
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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13+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Carboxypeptidase E, how selective are they, and which programs against it are still in active trials?

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