Protein c-Fos

BE0001126ProteinHumansFOS

Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. It is acted on by 2 drugs in DrugBank.

Gene name
FOS
UniProtKB entry
P01100Swiss-Prot
Cellular location
Nucleus
Residues / weight
380 residues · 40,695 Da
Also known as
Cellular oncogene fos · Fos proto-oncogene, AP-1 transcription factor subunit · G0/G1 switch regulatory protein 7 · G0S7 · Proto-oncogene c-Fos

Resolves to

Protein
UniProtP01100UniProt nameFOS_HUMAN
Gene
HGNCHGNC:3796NCBI Gene2353GenBank29904GeneCardsFOS
Pharmacology
KEGGhsa:2353
Structure
PDB1A02PDB1FOSPDB1S9K
Drugs

What you can answer from here — as of September 03, 2024

2DrugsApproved to experimental, with action, bond type and pharmacological action
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6Clinical trialsTrials of drugs acting on it, by phase and status
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20GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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21+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Protein c-Fos, how selective are they, and which programs against it are still in active trials?

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