Fibronectin

BE0001180ProteinHumansFN1

Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin (PubMed:3024962, PubMed:3593230, PubMed:3900070, PubMed:7989369). It is acted on by 13 drugs in DrugBank.

Gene name
FN1
UniProtKB entry
P02751Swiss-Prot
Cellular location
Secreted, extracellular space, extracellular matrix
Residues / weight
2,477 residues · 272,319 Da
Also known as
CIG · Cold-insoluble globulin · FN

Resolves to

Protein
UniProtP02751UniProt nameFINC_HUMAN
Gene
HGNCHGNC:3778NCBI Gene2335GenBank12053817GeneCardsFN1
Pharmacology
KEGGhsa:2335
Structure
PDB1E88PDB1E8BPDB1FBR
Drugs

What you can answer from here — as of September 07, 2019

13DrugsApproved to experimental, with action, bond type and pharmacological action
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10Clinical trialsTrials of drugs acting on it, by phase and status
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23GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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92+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Fibronectin, how selective are they, and which programs against it are still in active trials?

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