Tumor necrosis factor receptor superfamily member 5

BE0001196ProteinHumansCD40

Receptor for TNFSF5/CD40LG (PubMed:31331973). It is acted on by 12 drugs in DrugBank.

Gene name
CD40
UniProtKB entry
P25942Swiss-Prot
Cellular location
Cell membrane
Residues / weight
277 residues · 30,619 Da
Also known as
B-cell surface antigen CD40 · Bp50 · CD40L receptor · CDw40 · TNFRSF5

Resolves to

Protein
UniProtP25942UniProt nameTNR5_HUMAN
Gene
HGNCHGNC:11919NCBI Gene958GenBank29851GeneCardsCD40
Pharmacology
IUPHAR/GtoPdb1874KEGGhsa:958
Structure
PDB1CZZPDB1D00PDB1FLL
Drugs

What you can answer from here — as of September 07, 2019

12DrugsApproved to experimental, with action, bond type and pharmacological action
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5Clinical trialsTrials of drugs acting on it, by phase and status
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13GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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48+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Tumor necrosis factor receptor superfamily member 5, how selective are they, and which programs against it are still in active trials?

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