Listeriolysin regulatory protein

BE0001233ProteinListeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)prfA

Positively regulates expression of listeriolysin, of 1-phosphadidylinositol phosphodiesterase (PI-PLC) and other virulence factors. It is acted on by 3 drugs in DrugBank.

Gene name
prfA
UniProtKB entry
P22262Swiss-Prot
Cellular location
Cytoplasmic
Residues / weight
237 residues · 27,301 Da

Resolves to

Protein
UniProtP22262UniProt namePRFA_LISMO
Gene
NCBI Gene987031GenBank48960
Pharmacology
KEGGlmo:lmo0200
Structure
PDB1OMIPDB2BEOPDB2BGC
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
5GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
9+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Listeriolysin regulatory protein, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In