Sulfotransferase 2B1

BE0001264ProteinHumansSULT2B1

Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation. It is acted on by 6 drugs in DrugBank.

Gene name
SULT2B1
UniProtKB entry
O00204Swiss-Prot
Cellular location
Cytoplasm, cytosol
Residues / weight
365 residues · 41,307 Da
Also known as
2.8.2.2 · Alcohol sulfotransferase · HSST2 · Hydroxysteroid sulfotransferase 2 · ST2B1

Resolves to

Protein
UniProtO00204UniProt nameST2B1_HUMAN
Gene
HGNCHGNC:11459NCBI Gene6820GenBank1923291GeneCardsSULT2B1
Pharmacology
KEGGhsa:6820
Structure
PDB1Q1QPDB1Q1ZPDB1Q20
Drugs

What you can answer from here — as of September 03, 2024

6DrugsApproved to experimental, with action, bond type and pharmacological action
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10GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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17+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Sulfotransferase 2B1, how selective are they, and which programs against it are still in active trials?

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