Apolipoprotein(a)

BE0001283ProteinHumansLPA

Apo(a) is the main constituent of lipoprotein(a) (Lp(a)). It is acted on by 4 drugs in DrugBank.

Gene name
LPA
UniProtKB entry
P08519Swiss-Prot
Residues / weight
2,040 residues · 226,544 Da
Also known as
3.4.21.- · Apo(a) · Lp(a)

Resolves to

Protein
UniProtP08519UniProt nameAPOA_HUMAN
Gene
HGNCHGNC:6667NCBI Gene4018GenBank28620GeneCardsLPA
Pharmacology
KEGGhsa:4018
Structure
PDB1I71PDB1JFNPDB1KIV
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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2Clinical trialsTrials of drugs acting on it, by phase and status
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1GO termFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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19+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Apolipoprotein(a), how selective are they, and which programs against it are still in active trials?

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