Muvalaplin

DB21568InvestigationalSmall molecule

Muvalaplin is a small molecule drug. Muvalaplin is under investigation in clinical trial NCT05563246 (A Study of LY3473329 in Adult Participants With Elevated Lipoprotein(a) at High Risk for Cardiovascular Events).... Muvalaplin has a monoisotopic molecular weight of 710.4 Da.

Chemical structure of Muvalaplin
Formula / weight
C42H54N4O6 · 710.916 g/mol (avg)
Code names
LY-3473329

Resolves to

Structure
InChIKeyBRLGERLDHZRETI-BGBFCPIGSA-NSMILES[H][C@@]1(CCNC1)[C@H](CC1=CC(CN(CC2=CC(C[C@H](C(O)=O)[C@@]3([H])CCNC3)=CC=C2)CC2=CC(C[C@H](C(O)=O)[C@@]3([H])CCNC3)=CC=C2)=CC=C1)C(O)=O
Targets

What you can answer from here — as of September 23, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
Listed above
4Clinical trialsPhase, status and sponsor resolved per trial
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1+ReferenceStructured and connected to the statements they support
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Which drugs share a target with Muvalaplin, and which of those have an active Phase 3 trial?

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