Dihydroneopterin aldolase

BE0001289ProteinStaphylococcus aureusfolB

Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin. It is acted on by 10 drugs in DrugBank.

Gene name
folB
UniProtKB entry
P56740Swiss-Prot
Residues / weight
121 residues · 13,751 Da
Also known as
4.1.2.25 · 7,8-dihydroneopterin 2'-epimerase · 7,8-dihydroneopterin aldolase · 7,8-dihydroneopterin epimerase · DHNA

Resolves to

Protein
UniProtP56740UniProt nameFOLB_STAAU
Structure
PDB1DHNPDB1RRIPDB1RRW
Drugs

What you can answer from here — as of September 07, 2019

10DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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18+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Dihydroneopterin aldolase, and which indications are they being tested in?

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