ADP-L-glycero-D-manno-heptose-6-epimerase

BE0001296ProteinEscherichia coli (strain K12)hldD

Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose. It is acted on by 2 drugs in DrugBank.

Gene name
hldD
UniProtKB entry
P67910Swiss-Prot
Residues / weight
310 residues · 34,893 Da
Also known as
5.1.3.20 · ADP-glyceromanno-heptose 6-epimerase · ADP-hep 6-epimerase · ADP-L-glycero-beta-D-manno-heptose-6-epimerase · AGME

Resolves to

Protein
UniProtP67910UniProt nameHLDD_ECOLI
Gene
NCBI Gene948134GenBank147576
Pharmacology
KEGGecj:JW3594
Structure
PDB1EQ2PDB2X6T
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
6GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
18+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on ADP-L-glycero-D-manno-heptose-6-epimerase, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In